Data last refreshed August 18th, 2026Prices and terms were read from each provider’s own site on that date and change often, sometimes weekly. Re-checked twice a month; next refresh due September 2nd, 2026.

Tirzepatide providers: what a month really costs

Tirzepatide is a legal, approved medicine, so the question is not whether a seller is real. It is what you will actually pay once the introductory rate ends — and that turns out to be remarkably hard to find out. Of the 21 providers here, only 9 publish what a 10 mg maintenance dose costs. The rest advertise a starting price and tell you the rest after you have handed over your medical history.

Evo does not sell medication and has no commercial relationship with anyone listed here. There are no affiliate links on this page and no provider paid to appear. That matters more in this market than most: clicks on these searches sell for $30 to $46, and most of the competing “cheapest provider” guides are paid by commission.

We publish the raw data.Every figure was read from the provider’s own site, with the source recorded — prices, fees, commitment terms, what is in the syringe, and how each rating was calculated. Download the full capture (JSON) and check any row, or re-weight the rating to suit your own priorities.

Twenty online tirzepatide providers with Evo Rating, real monthly cost at a maintenance dose, what is in the syringe and provider type, captured August 18th, 2026.
#	Provider	Evo Rating / 5	Real cost at 10 mg	In the syringe	Type
1	LillyDirectlilly.com · visibility #1	2.92.92 out of 5 stars	$488/mo	Nothing added	FDA-approved
2	Walgreenswalgreens.com · visibility #2	2.92.92 out of 5 stars	$488/mo	Nothing added	FDA-approved
3	PlexusDxplexusdx.com · visibility #12	2.82.81 out of 5 stars	$289/mo	B12	Compounded
4	Sesamesesamecare.com · visibility #6	2.72.74 out of 5 stars	$449/mo	Nothing added	FDA-approved
5	Roro.co · visibility #5	2.32.34 out of 5 stars	$562/mo	Nothing added	FDA-approved
6	Foundjoinfound.com · visibility #20	2.32.34 out of 5 stars	$650/mo	Nothing added	FDA-approved
7	Amazon Pharmacypharmacy.amazon.com · visibility #21	2.32.33 out of 5 stars	$1,113/mo	Nothing added	FDA-approved
8	CallOnDoccallondoc.com · visibility #18	2.12.13 out of 5 stars	—Doesn't sell the drug	Nothing added	Prescription only
9	Fridaysjoinfridays.com · visibility #15	1.91.85 out of 5 stars	$275/mo	—Undisclosed	Compounded
10	TrumpRxtrumprx.gov · visibility #3	1.71.69 out of 5 stars	—Sends you to LillyDirect	Nothing added	FDA-approved
11	Vitastirvitastir.com · visibility #13	1.61.64 out of 5 stars	$449/mo	B12 + glycine	Compounded
12	Hims & Hersforhers.com · visibility #9	1.51.5 out of 5 stars	—Site blocks all reads	Nothing added	FDA-approved
13	WeightWatchersweightwatchers.com · visibility #10	1.51.5 out of 5 stars	—Only a 'starting at' price	Nothing added	FDA-approved
14	Pomegranate Healthjoinpomegranate.com · visibility #7	1.21.19 out of 5 stars	—Only a 'starting at' price	B6	Compounded
15	ShedRxshedrx.com · visibility #11	0.80.84 out of 5 stars	—Only a 'starting at' price	B12	Compounded
16	Brellobrellohealth.com · visibility #8	0.80.75 out of 5 stars	—Behind a medical intake	B6	Compounded
17	Empower Pharmacyempowerpharmacy.com · visibility #19	0.80.75 out of 5 stars	—Doesn't sell the drug	niacinamide	Compounded
18	Lavender Sky Healthlavenderskyhealth.com · visibility #16	0.30.25 out of 5 stars	—Only a 'starting at' price	—Undisclosed	Compounded
19	Alloymyalloy.com · visibility #4	0.20.19 out of 5 stars	—Behind a medical intake	—Undisclosed	Compounded
20	Shapelygetshapely.com · visibility #14	0.20.19 out of 5 stars	—Doesn't sell the drug	—Undisclosed	Prescription only
21	TrimRxtrimrx.com · visibility #17	0.00 out of 5 stars	—Behind a medical intake	—Undisclosed	Compounded

A dash means the provider does not publish it, not that we did not look — the text under each dash says why. We checked for a machine-readable price on every one of them (Shopify product data, the WooCommerce store API, embedded page data) and not a single provider exposes one, because here the price is the thing you trade your medical history for. “Real cost at 10 mg” is the all-in monthly figure: medication plus any mandatory membership, adjusted for how many times a year you are actually billed. 5 providers do not say what is in their product at all, which caps their rating at 2.5however cheap they are. Every provider the FDA has written to about its tirzepatide marketing has been removed from the table entirely — they are listed under what we excluded, below.

What each rating is made of

Every point below comes from something published on the provider’s own site. Nothing is an editorial impression, and no rating is entered by hand.

LillyDirect

2.9

Real monthly cost +0.8
About $488 a month all in at 10 mg.
What is in the syringe +1.5
The FDA-approved drug, with nothing added.
Easy to leave +0.375
Offers cancel without a phone call, advertised rate without prepaying a block. Does not: price held as the dose escalates. Not stated: refunds unused prepaid months.
Price published up front +0.25
Prices are readable without starting an intake questionnaire.

Starting dose: 2.5 mg is a starting dose and is not approved as a maintenance dose.

At maintenance: $449 only if the prescription is refilled within 45 days. Miss that window and 10 mg is $699. A month is defined as 28 days, so this bills about 13 times a year, not 12.

The benchmark: the approved drug from the manufacturer, no membership and no prepay. The 45-day refill cliff is the only trap, and it is a $250 one.

Walgreens

2.9

Real monthly cost +0.8
About $488 a month all in at 10 mg.
What is in the syringe +1.5
The FDA-approved drug, with nothing added.
Easy to leave +0.375
Offers cancel without a phone call, advertised rate without prepaying a block. Does not: price held as the dose escalates. Not stated: refunds unused prepaid months.
Price published up front +0.25
Prices are readable without starting an intake questionnaire.

At maintenance: The Lilly self-pay programme filled at Walgreens, and that programme defines a month as 28 days. Walgreens' own page does not say so.

Visits are billed separately at $49 for the first and $49 for each follow-up. No subscription.

PlexusDx

2.8

Real monthly cost +1.6
About $289 a month all in at 10 mg.
What is in the syringe +0.4
Compounded with B12. B12 analogs are the combination shown to react with tirzepatide and form a novel impurity.
Easy to leave +0.5625
Offers cancel without a phone call, price held as the dose escalates, advertised rate without prepaying a block. Not stated: refunds unused prepaid months.
Price published up front +0.25
Prices are readable without starting an intake questionnaire.

Starting dose: Month-to-month rate; lower on longer commitment tiers.

At maintenance: Flat across every dose from 2.5 mg to 15 mg — the site's own line is 'Doses go up. Your price won't.'

Also publishes affiliate-style 'best provider' roundups that rank its own product, which is worth knowing if you meet one in search results.

Sesame

2.7

Real monthly cost +0.8
About $449 a month all in at 10 mg.
What is in the syringe +1.5
The FDA-approved drug, with nothing added.
Easy to leave +0.1875
Offers advertised rate without prepaying a block. Not stated: cancel without a phone call, refunds unused prepaid months, price held as the dose escalates.
Price published up front +0.25
Prices are readable without starting an intake questionnaire.

At maintenance: $399/mo for 5 mg, $449/mo for all other doses.

Publishes LillyDirect's cash prices openly on its own page, which is more transparency about someone else than most compounders manage about themselves.

Ro

2.3

Real monthly cost +0.4
About $562 a month all in at 10 mg, including the Ro Body membership.
What is in the syringe +1.5
The FDA-approved drug, with nothing added.
Easy to leave +0.1875
Offers cancel without a phone call. Does not: price held as the dose escalates, advertised rate without prepaying a block. Not stated: refunds unused prepaid months.
Price published up front +0.25
Prices are readable without starting an intake questionnaire.

Starting dose: The $74 membership is the prepaid rate; it is higher month to month.

At maintenance: Publishes the whole Lilly ladder, including what happens if you miss the 45-day window: $499 for a 7.5 mg refill and $699 for 10, 12.5 and 15 mg. The membership is charged on top.

The most honest pricing page of any reseller here: it publishes the penalty prices its own supplier buries in a footnote.

Found

2.3

Real monthly cost +0.4
About $650 a month all in at 10 mg.
What is in the syringe +1.5
The FDA-approved drug, with nothing added.
Easy to leave +0.1875
Offers advertised rate without prepaying a block. Not stated: cancel without a phone call, refunds unused prepaid months, price held as the dose escalates.
Price published up front +0.25
Prices are readable without starting an intake questionnaire.

Starting dose: Zepbound listed 'from $650/mo+', with the plus doing real work — Mounjaro is listed at $1,100/mo.

At maintenance: Quoted as a floor rather than a dose-specific price.

Publishes brand prices well above what the manufacturer charges direct, which is the clearest argument on this page for checking LillyDirect first.

Amazon Pharmacy

2.3

Real monthly cost +0.2
About $1,113 a month all in at 10 mg.
What is in the syringe +1.5
The FDA-approved drug, with nothing added.
Easy to leave +0.375
Offers cancel without a phone call, advertised rate without prepaying a block. Not stated: refunds unused prepaid months, price held as the dose escalates.
Price published up front +0.25
Prices are readable without starting an intake questionnaire.

Starting dose: Retail price without insurance. Listed at $25 with insurance, which depends entirely on your plan.

At maintenance: Retail list price, not a self-pay programme rate.

The retail reference point: the same approved drug at more than double LillyDirect's self-pay price if you have no insurance.

CallOnDoc

2.1

Real monthly cost +0
No maintenance-dose price is published, so the real cost could not be established.
What is in the syringe +1.5
The FDA-approved drug, with nothing added.
Easy to leave +0.375
Offers cancel without a phone call, advertised rate without prepaying a block. Does not: refunds unused prepaid months. Not stated: price held as the dose escalates.
Price published up front +0.25
Prices are readable without starting an intake questionnaire.

Starting dose: $75 for the visit. The prescription is filled at a pharmacy of your choice and the drug billed there.

At maintenance: Medication is not supplied, so no maintenance price exists here.

A prescription service rather than a supplier: one flat $75 visit fee, stated non-refundable, no subscription.

Fridays

1.9

Real monthly cost +1.6
About $275 a month all in at 10 mg.
What is in the syringe +0
The provider does not say what its compounded product contains.
Easy to leave +0
Does not: refunds unused prepaid months, advertised rate without prepaying a block. Not stated: cancel without a phone call, price held as the dose escalates.
Price published up front +0.25
Prices are readable without starting an intake questionnaire.

Capped tier: the provider does not disclose what is in its compounded product. A provider in this position cannot score above 2.5 however cheap it is.

Starting dose: $1,650 for a six-month supply, which is $275 a month, payable up front.

At maintenance: Sold as a six-month block rather than by dose.

Commitment: the advertised rate needs 6 months.

The six-month block is the headline offer and the page states it is non-refundable.

TrumpRx

1.7

Real monthly cost +0
No maintenance-dose price is published, so the real cost could not be established.
What is in the syringe +1.5
The FDA-approved drug, with nothing added.
Easy to leave +0.1875
Offers advertised rate without prepaying a block. Not stated: cancel without a phone call, refunds unused prepaid months, price held as the dose escalates.
Price published up front +0
Pricing is not shown until you begin an intake questionnaire.

Starting dose: The federal site advertises 'up to 72% off' and does not publish a price for any dose. Its own page states that Eli Lilly manages all Zepbound vial orders through LillyDirect.

At maintenance: No price is published here. You are handed to LillyDirect, so the figure you actually pay is the LillyDirect one in the row above — including the 45-day refill condition.

Included because a lot of people now start here, and the useful thing to know is that it is a front door rather than a pharmacy. It sets no price of its own, and eligibility is deferred to Lilly's terms — reporting through 2026 has consistently described the GLP-1 discounts as unavailable to anyone on government or federally funded drug coverage, so check before assuming it applies to you.

Vitastir

1.6

Real monthly cost +0.8
About $449 a month all in at 10 mg.
What is in the syringe +0.4
Compounded with B12 + glycine. B12 analogs are the combination shown to react with tirzepatide and form a novel impurity.
Easy to leave +0.1875
Offers advertised rate without prepaying a block. Does not: price held as the dose escalates. Not stated: cancel without a phone call, refunds unused prepaid months.
Price published up front +0.25
Prices are readable without starting an intake questionnaire.

Starting dose: $145 for four 2.5 mg injections.

At maintenance: Publishes the whole ladder, which almost nobody here does: 2.5 mg $145, 5 mg $299, 7.5 mg $399, 10 mg $449, 12.5 mg $499, 15 mg $599. Shipping is charged separately at about $22.

The only compounder here that publishes a price for every dose, and it shows the usual pattern: cheap to start, level with the brand by maintenance.

Hims & Hers

1.5

Real monthly cost +0
No maintenance-dose price is published, so the real cost could not be established.
What is in the syringe +1.5
The FDA-approved drug, with nothing added.
Easy to leave +0
Not stated: cancel without a phone call, refunds unused prepaid months, price held as the dose escalates, advertised rate without prepaying a block.
Price published up front +0
Pricing is not shown until you begin an intake questionnaire.

At maintenance: Every request from here answers HTTP 403, including from a real browser session, so nothing could be established either way.

The row is deliberately blank rather than guessed.

WeightWatchers

1.5

Real monthly cost +0
No maintenance-dose medication price is published. The Med+ membership is $74 a month on top of whatever the drug costs.
What is in the syringe +1.5
The FDA-approved drug, with nothing added.
Easy to leave +0
Does not: advertised rate without prepaying a block. Not stated: cancel without a phone call, refunds unused prepaid months, price held as the dose escalates.
Price published up front +0
Pricing is not shown until you begin an intake questionnaire.

Starting dose: Self-pay Zepbound single-dose vial from $349/month, plus membership: $25 for the first month, then $74/month on the 12-month plan or $84 on the 6-month.

At maintenance: The $349 figure is 'starting at'; no maintenance-dose price is published.

Commitment: the advertised rate needs 6 months.

The $25 first month requires a 6- or 12-month plan and renews at full rate unless cancelled.

Pomegranate Health

1.2

Real monthly cost +0
No maintenance-dose price is published, so the real cost could not be established.
What is in the syringe +0.75
Compounded with B6, disclosed on the product page.
Easy to leave +0.1875
Offers advertised rate without prepaying a block. Not stated: cancel without a phone call, refunds unused prepaid months, price held as the dose escalates.
Price published up front +0.25
Prices are readable without starting an intake questionnaire.

Starting dose: Listed as 'Tirzepatide + Pyridoxine (B6)' at $149/month on the Starter tier.

At maintenance: The $149 rate is the Starter tier; no price is published for a maintenance dose.

One of the few that names its additive in the product title rather than in the small print.

ShedRx

0.8

Real monthly cost +0
No maintenance-dose price is published, so the real cost could not be established.
What is in the syringe +0.4
Compounded with B12. B12 analogs are the combination shown to react with tirzepatide and form a novel impurity.
Easy to leave +0.1875
Offers advertised rate without prepaying a block. Not stated: cancel without a phone call, refunds unused prepaid months, price held as the dose escalates.
Price published up front +0.25
Prices are readable without starting an intake questionnaire.

Starting dose: The pricing page says compounded tirzepatide starts at $349/month. The home page advertises 'as low as $239/mo', which is a promotional rate we could not reproduce at the pricing page.

At maintenance: No dose-specific pricing published.

Two different starting prices on two pages of the same site: $239 on the home page, $349 on the pricing page. A third figure, $229, appears in the page data at /tirzepatide but belongs to its GLP-1 liquid drops rather than to tirzepatide, which is the kind of thing that turns into a wrong number if you scrape without reading.

Brello

0.8

Real monthly cost +0
No maintenance-dose price is published, so the real cost could not be established.
What is in the syringe +0.75
Compounded with B6, disclosed on the product page.
Easy to leave +0
Does not: refunds unused prepaid months, advertised rate without prepaying a block. Not stated: cancel without a phone call, price held as the dose escalates.
Price published up front +0
Pricing is not shown until you begin an intake questionnaire.

Starting dose: Advertised as $166/month. It is $499 billed today, then $499 every 11 weeks — not every 12 — so it renews about 4.7 times a year rather than 4.

At maintenance: No dose-specific pricing published.

Commitment: the advertised rate needs 3 months.

If the health review declines you, the refund is your payment minus a $50 professional fee.

Empower Pharmacy

0.8

Real monthly cost +0
No maintenance-dose price is published, so the real cost could not be established.
What is in the syringe +0.75
Compounded with niacinamide, disclosed on the product page.
Easy to leave +0
Not stated: cancel without a phone call, refunds unused prepaid months, price held as the dose escalates, advertised rate without prepaying a block.
Price published up front +0
Pricing is not shown until you begin an intake questionnaire.

At maintenance: Dispensed only against a patient-specific prescription; no consumer price is published.

The compounding pharmacy behind other people's brands rather than a direct seller. Included because it names its additive plainly, which most of its customers' front ends do not.

Lavender Sky Health

0.3

Real monthly cost +0
No maintenance-dose price is published, so the real cost could not be established.
What is in the syringe +0
The provider does not say what its compounded product contains.
Easy to leave +0
Does not: advertised rate without prepaying a block. Not stated: cancel without a phone call, refunds unused prepaid months, price held as the dose escalates.
Price published up front +0.25
Prices are readable without starting an intake questionnaire.

Capped tier: the provider does not disclose what is in its compounded product. A provider in this position cannot score above 2.5 however cheap it is.

Starting dose: Prices are published as tiers of total milligrams over an 8-to-10-week supply rather than per dose, and the published tiers correspond to semaglutide dosing, so no tirzepatide figure could be read off them with confidence.

At maintenance: Same: the tier structure does not map cleanly onto a tirzepatide maintenance dose.

Commitment: the advertised rate needs 2 months.

Unusually, it names the compounding pharmacies it uses — Empower and Strive — which almost nobody else does. Its pricing is detailed but structured in a way we could not translate into a per-dose figure, so those cells are blank rather than guessed.

Alloy

0.2

Real monthly cost +0
No maintenance-dose medication price is published. The Alloy Weight Care is $99 a month on top of whatever the drug costs.
What is in the syringe +0
The provider does not say what its compounded product contains.
Easy to leave +0.1875
Offers advertised rate without prepaying a block. Not stated: cancel without a phone call, refunds unused prepaid months, price held as the dose escalates.
Price published up front +0
Pricing is not shown until you begin an intake questionnaire.

Capped tier: the provider does not disclose what is in its compounded product. A provider in this position cannot score above 2.5 however cheap it is.

Starting dose: The $100 headline is medication only. Alloy Weight Care is $99/month on top and is not optional, so the real starting cost is $199.

At maintenance: No price published for 10 mg — the page says only 'starting at $100'.

Not available in: AL, AR, CA, NV, LA, MS, DC

Ranked top three on five of the six buying queries we measured, on a $100 price that is really $199.

Shapely

0.2

Real monthly cost +0
No maintenance-dose medication price is published. The Shapely membership is $99 a month on top of whatever the drug costs.
What is in the syringe +0
The provider does not say what its compounded product contains.
Easy to leave +0.1875
Offers advertised rate without prepaying a block. Not stated: cancel without a phone call, refunds unused prepaid months, price held as the dose escalates.
Price published up front +0
Pricing is not shown until you begin an intake questionnaire.

Capped tier: the provider does not disclose what is in its compounded product. A provider in this position cannot score above 2.5 however cheap it is.

Starting dose: $99/month membership, $49 for the first. Medication is explicitly not included.

At maintenance: Medication billed separately by whichever pharmacy fills it.

The membership buys telehealth access, not medicine. Labs are a further $75 without insurance.

TrimRx

0.0

Real monthly cost +0
No maintenance-dose price is published, so the real cost could not be established.
What is in the syringe +0
The provider does not say what its compounded product contains.
Easy to leave +0
Not stated: cancel without a phone call, refunds unused prepaid months, price held as the dose escalates, advertised rate without prepaying a block.
Price published up front +0
Pricing is not shown until you begin an intake questionnaire.

Capped tier: the provider does not disclose what is in its compounded product. A provider in this position cannot score above 2.5 however cheap it is.

Starting dose: Advertised as 'plans from $179/mo'; the conditions attached are not stated before intake.

At maintenance: No dose-specific pricing published.

How this page was built

Which providers are listed.We measured who is actually visible rather than picking names. Six buying-intent Google queries — “cheapest tirzepatide”, “buy tirzepatide online”, “compounded tirzepatide”, “tirzepatide without insurance”, “where to buy tirzepatide” and “tirzepatide for sale” — were pulled through a rank-tracking API, and every commerce domain in those results was recorded. Editorial and affiliate roundups were discarded; only providers that actually sell or prescribe are in the table.

Where the numbers come from.A scraper reads each provider’s own pricing page for prices with the sentences around them, because a bare figure is useless here — whether $299 is per month, per quarter or per starting dose is the entire question. Every figure was then confirmed by hand, and several pages had to be read in a browser because they refuse automated requests. Anything still unestablished is blank.

What we could not get. This page has more blanks than our others, and that is the finding rather than a gap in the work. Most providers that hide a maintenance price do so behind an intake questionnaire, which we did not complete: filling in a medical history to extract a price would mean submitting false information, and we are not going to do that to write a table. Where a price could be found by digging — a separate pricing page, a titration schedule, a footnote — we dug, and several rows that were blank on the first pass now carry a figure.

The FDA letters. There are 109 warning letters naming tirzepatide, and 85 of the 100 most recent target telehealth companies — for misleading claims or for selling unapproved drugs online. Forty were issued in 2025 and sixty more in 2026. Any provider named in one is removed from this table rather than flagged in it: a capped rating still puts a company in front of you as an option, and these are the companies the agency has actually looked at.

Finding them takes a particular route, because the index does not search letter bodies and a domain query returns nothing. We queried the compound instead, then opened each candidate letter and confirmed the website it names before excluding anyone on that basis. Five providers came out that way, including two that would otherwise have been among the cheapest here.

What we removed. Every provider the FDA has written to about its tirzepatide marketing, providers outside the United States, sites that could not be reached at all, one that advertises GLP-1 treatment but sells no tirzepatide, and one selling it as a laboratory reagent rather than for human use:

fifty410.com — FDA warning letter, 20 February 2026, over claims for its compounded semaglutide and tirzepatide. The letter names fifty410.com. Read the letter.
ivimhealth.com — FDA warning letter, 20 February 2026, over claims for its compounded semaglutide and tirzepatide. The letter names ivimhealth.com. Read the letter.
remedymeds.com — FDA warning letter, 9 September 2025, over claims concerning its compounded semaglutide and tirzepatide. The letter names remedymeds.com. Read the letter.
tryeden.com — FDA warning letter, 8 June 2026, over its website's claims for compounded semaglutide and tirzepatide. The letter names tryeden.com. Read the letter.
medvi.com — FDA warning letter, 20 February 2026. Considered as a replacement and rejected for the same reason.
israelpharm.com — Ships from outside the United States, so a different regulatory regime applies.
henrymeds.com — Advertises GLP-1 treatment from $179/month but no tirzepatide product could be found on the site.
mochihealth.com — Site could not be reached from here at capture.
zealthy.com — Site could not be reached from here at capture.
adipogen.com — Sells tirzepatide as a laboratory reagent, not for human use.

What this page cannot tell you. Nothing here is a judgement of clinical care — we have not seen a consultation, and a cheap provider with a good rating may still be the wrong choice for you. Prices are promotional and move constantly. And a rating is a weighted opinion about which trade-offs matter: ours puts cost first and contents second, which may not be your order. The raw data exists so you can use your own.

Questions people ask

Answered from the FDA’s own statements, published research, and what we captured from the providers themselves. Where the honest answer is that nobody publishes it, it says so.

How does tirzepatide work?

Tirzepatide is a single molecule that activates two receptors: GIP and GLP-1. That dual action is what separates it from semaglutide, which acts on GLP-1 alone. It slows how quickly the stomach empties, acts on the appetite centres of the brain, and improves the insulin response after eating.

It is given as a once-weekly injection under the skin, and the dose is escalated gradually over months because side effects track the dose closely. Unlike most of what this site covers, tirzepatide is an approved medicine with published Phase 3 trials behind it — sold as Zepbound for weight management and Mounjaro for type 2 diabetes.

What does tirzepatide actually cost per month?

That is the question this page exists to answer, and the honest headline is that most providers will not tell you. Of the 21 we checked on August 18th, 2026, only 9 publish what a 10 mg maintenance dose costs. The rest advertise a starting price and reveal the rest after you have completed a medical questionnaire.

Among those that do publish, the range at maintenance runs from about $275 a month for a compounded product to $488 for the FDA-approved drug bought direct from the manufacturer.

Three things move the real number a long way from the advertised one. A mandatory membership fee is often quoted separately from the medication. A 'monthly' price frequently means a quarter or half-year paid up front. And the billing period may not be a calendar month at all — LillyDirect defines a month as 28 days, so you are billed about thirteen times a year, and one provider renews every eleven weeks.

Is compounded tirzepatide legal?

The legal footing it once had has gone. Mass compounding of tirzepatide was permitted because the drug was in shortage; the FDA declared that shortage resolved on 2 October 2024, and with it the basis for compounding copies.

Providers continue to sell it by not selling a copy. A pharmacy may not compound something that is essentially a copy of an approved drug, so products are sold as tirzepatide combined with a vitamin — B12, B6, niacinamide — and marketed as 'personalized'. The additive is there for a legal reason rather than a clinical one.

This is a description of how the market is regulated and not legal advice. It is also moving: the position stated here is as of the capture date at the top of this page.

FDA — concerns with unapproved GLP-1 drugs used for weight loss

Is compounded tirzepatide the same as Zepbound or Mounjaro?

No. Compounded products are not FDA-approved, are not made to the same manufacturing standards, and in most cases are not the same molecule in the syringe — because of the vitamin they are mixed with.

A 2026 paper in Expert Opinion on Drug Safety tested compounded tirzepatide/B12 products and reported a previously unidentified impurity, present at substantial levels, formed by a chemical reaction between tirzepatide and certain B12 analogs. The clinical effect of that impurity is unknown.

One caveat matters as much as the finding: every author of that paper works for Eli Lilly, which holds the patent and sells the competing approved product. It is peer-reviewed and the chemistry is checkable, but it has not been independently replicated, and the loudest safety voice in this market being the patent holder is part of the picture. We have weighted the B12 combination accordingly in the rating rather than treating all compounding as equivalent.

Jordan et al., Expert Opinion on Drug Safety (2026) — authors are Eli Lilly employees · FDA — concerns with unapproved GLP-1 drugs used for weight loss

What happened to the providers with FDA warning letters?

They are not in the table. There are 109 FDA warning letters naming tirzepatide, and 85 of the 100 most recent target telehealth companies — for false or misleading claims, or for selling unapproved and misbranded drugs online. Forty were issued in 2025 and sixty more in 2026, so this is an active sweep rather than a historical footnote.

4 providers were removed on that basis and are listed under what we excluded, with a link to each letter. Two of them would otherwise have been among the cheapest on this page, which is precisely why they are not simply flagged and left in: a low price next to a warning badge still reads as an option.

The absence of a letter is not a clean bill of health. It means the agency has not published one naming that company over tirzepatide, and plenty of sellers have simply not been reviewed yet.

FDA — concerns with unapproved GLP-1 drugs used for weight loss

Is the approved drug more expensive than compounded?

Less than the advertising suggests, and sometimes not at all. The gap between the cheapest published compounded maintenance price and the manufacturer's own self-pay price is real but much narrower than a "$100 a month" headline implies — because those headlines routinely exclude a mandatory membership, assume a prepaid block, or quote the 2.5 mg starting dose you will only be on for a few weeks.

The clearest example in our table advertises tirzepatide at $100 a month. The medication is $100; the mandatory care membership is another $99, so the real figure is $199, and no price is published for a maintenance dose at all.

Whether the approved drug is worth the difference is your call, not ours. What this page can do is make the two numbers comparable.

What does the Evo Rating measure?

Three things, weighted: what a month really costs at a maintenance dose (2.0 points), what is actually in the syringe (1.5), how easy the provider is to leave (1.0), and whether the price is published before you hand over your medical history (0.5).

It is deliberately not the Evo Trust Score used on our retatrutide and BPC-157 tables. Those score whether a seller's claims can be verified at all, which is the right question in a market with no legal channel. Here you can buy an approved drug with a prescription, so the open questions are cost, contents and friction. A 4 on this page and a 4 on those pages do not mean the same thing.

Every component and its reasoning is published in the raw data, so if you think price should count for more than we gave it, you can recompute the whole table rather than just disagree with it.

Does Evo sell tirzepatide or earn commission from these providers?

No. Evo does not sell medication, has no commercial relationship with any provider listed, and takes nothing from anyone on this page. There are no affiliate links here and no provider paid to appear.

That is worth stating plainly in this market in particular. Clicks on these terms sell for $30 to $46, most of the competing 'cheapest provider' roundups are monetised by affiliate commission, and at least one provider in our table publishes its own comparison articles ranking its own product. The full capture behind this table is published as JSON so you can check any row rather than trust ours.

Our tirzepatide calculator works out concentration and syringe units from a vial, presenting ranges and assumptions rather than recommendations. We keep comparable tables for retatrutide and BPC-157 — both unapproved compounds, both scored on verifiability rather than on price, and neither number comparable with the ratings above.

Tirzepatide provider comparison

What each rating is made of

How this page was built

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